Whether mindfulness-guided therapy can be a new direction for the rehabilitation of patients with Parkinson’s disease: a network meta-analysis of non-pharmacological alternative motor-/sensory-based interventions

Background The treatment for Parkinson’s disease (PD) consumes a lot of manpower and financial resources. Non-pharmacological alternative motor-/sensory-based interventions are optimized the rehabilitation PD patients. Mindfulness-based therapy shows ideal efficacy, but diversity brings difficulties to selection clinicians Methods Network meta-analysis in Bayesian framework was used evaluate efficacy non-pharmacological improving motor non-motor symptoms Results A total 58 studies (2,227 patients) were included. Compared with non-intervention group, qigong associated improved outcomes Timed Up Go (TUG) test (mean difference (MD) −5.54, 95% confidence interval (CI) −8.28 −2.77), UPDRS-I (MD −15.50, CI −19.93 −7.63). Differences between not significant PDQ-39, UPDRS-I, or UPDRS-II; however, superior dance −3.91, −6.90 −0.95), Tai Chi −3.54, −6.53 −0.69), acupuncture −6.75, −10.86 −2.70), music -3.91, −7.49 −0.48), exercise −6.49 −1.33) TUG test. Conclusion This network supports mindfulness-based (e.g., qigong, yoga, Chi) as preferred intervention rehabilitation. Systematic review registration https://inplasy.com/inplasy-2022-10-0109/ , INPLASY2022100109.